Altering Existing Genetic Variation
Genetic Drift
Genetic drift is a change in in genetic variation due to chance changes in allele frequencies. For example, genetic drift may occur as a matter of luck; one phenotype may simply never meet a member of the opposite sex in order to mate and produce offspring. Genetic drift is not affected [...]
Population geneticists primarily study allele and genotype frequencies. They use quantitative methods to analyze the frequency of alleles. For example, a population geneticist may study the frequency of certain patterns on the fur of wild cats, then will revisit the same population several generations later to find how the frequency of patterns has changed from [...]
Onset & Symptoms:
Personality changes
Forgetfulness
Involuntary movements
Begins in middle adulthood
Progresses over 15-20 years
Leads to loss of motor control and intellectual function
Treatments:
Nothing known to slow or stop the decline
Prevalence:
1 in 20,000 people
Famous People with the Disease:
Woody Guthrie
Heritability & Environmental Factors:
Caused by a dominant allele
Individuals with Huntington’s Disease have one dominant Huntington’s allele and one normal allele. It is [...]
Onset & Symtoms:
Mental retardation
Becomes apparent in infancy/very early childhood, but is variable
Excess of phenylpyruvic acid in urine
Treatments:
Specialized low-phenylalanine diet
Prevalence:
1 in 10,000 people
Famous People with the Disease:
Unknown
Heritability & Environmental Factors:
Caused by a recessive allele
PKU is caused by a recessive allele, meaning an individual must inherit two copies of the allele, one from each parent, in order [...]
Ribosomes are the location where translation takes place. Prokaryotic cells do not have compartmentalized organelles, and thus need only one type of ribosome. They have one type of ribosome that translates the mRNA in the cytoplasm. In eukaryotic cells, however, there are different kinds of ribosomes in different organelles. The most abundant type of ribosome [...]
P generation – the “Parent” generation; the point of reference on which Mendelian predictions are based. Similar to an “index case” in a pedigree.
F1 generation – the first generation children of the P generation.
F2 generation – the second generation children of the P generation; the grandchildren of the P generation.
Dominant – the allele that is [...]
In the earlier days of our knowledge regarding DNA, there were three possible models proposed for how DNA replication occurs. These three models were the conservative mechanism, the semi-conservative mechanism, and the dispersive mechanism. Currently, the only accepted model [...]
Ha ha, NOW I’ve got your attention. The little buggy roaches don’t even PEE! Check out the article to find out how and why. And people dare say that humans are higher up on the evolutionary ladder? I heard somewhere- I forget where exactly- that one might like to postulate that God is a cockroach. [...]
Testicular Tumors May Explain Why Some Diseases Are More Common In Children Of Older Fathers.
We all learned in biology and genetics classes that the age of a mother has more effect on genetic disorders than does the age of the father. For example, the occurrence of Down’s Syndrome is closely tied to mothers over the [...]
Here is an interesting bit of new research regarding the genetics of age-related heart failure. For those who don’t want to read the whole scientific article, I have condensed the main points into a bullet point list under the link.
via Suppressing A Gene In Mice Prevents Heart From Aging, Preserves Its Function.
Aging causes changes in [...]
Top Articles